Is NMDA-Receptor-Mediated Oxidative Stress in Mitochondria of Peripheral Tissues the Essential Factor in the Pathogenesis of Hepatic Encephalopathy?

Background: Hepatic encephalopathy (HE) is a neuropsychiatric syndrome of increased ammonia-mediated brain dysfunction caused by impaired hepatic detoxification or when the blood bypasses the liver. Ammonia-activated signal transduction pathways of hyperactivated NMDA receptors (NMDAR) are shown to...

Descripción completa

Detalles Bibliográficos
Autores principales: Kosenko, Elena, Tikhonova, Lyudmila, Alilova, Gubidat, Montoliu, Carmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836479/
https://www.ncbi.nlm.nih.gov/pubmed/35160278
http://dx.doi.org/10.3390/jcm11030827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836479/
https://www.ncbi.nlm.nih.gov/pubmed/35160278
http://dx.doi.org/10.3390/jcm11030827

Ejemplares similares