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Oxidative DNA Damage and Cisplatin Neurotoxicity Is Exacerbated by Inhibition of OGG1 Glycosylase Activity and APE1 Endonuclease Activity in Sensory Neurons

Cisplatin can induce peripheral neuropathy, which is a common complication of anti-cancer treatment and negatively impacts cancer survivors during and after completion of treatment; therefore, the mechanisms by which cisplatin alters sensory neuronal function to elicit neuropathy are the subject of...

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Detalles Bibliográficos
Autores principales: Behrouzi, Adib, Xia, Hanyu, Thompson, Eric L., Kelley, Mark R., Fehrenbacher, Jill C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836551/
https://www.ncbi.nlm.nih.gov/pubmed/35163831
http://dx.doi.org/10.3390/ijms23031909