Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson’s Patient-Derived Neuronal Cells

Parkinson’s disease (PD) is neuropathologically characterized by the loss of dopaminergic neurons and the deposition of aggregated alpha synuclein (aSyn). Mounting evidence suggests that neuritic degeneration precedes neuronal loss in PD. A possible underlying mechanism could be the interference of...

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Detalles Bibliográficos
Autores principales: Seebauer, Lukas, Schneider, Yanni, Drobny, Alice, Plötz, Sonja, Koudelka, Tomas, Tholey, Andreas, Prots, Iryna, Winner, Beate, Zunke, Friederike, Winkler, Jürgen, Xiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836605/
https://www.ncbi.nlm.nih.gov/pubmed/35163733
http://dx.doi.org/10.3390/ijms23031812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836605/
https://www.ncbi.nlm.nih.gov/pubmed/35163733
http://dx.doi.org/10.3390/ijms23031812

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