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EZH2–CCF–cGAS Axis Promotes Breast Cancer Metastasis

Cytoplasmic chromatin fragments (CCF) are recognized by the cytoplasmic DNA sensor cyclic GMP-AMP synthase (cGAS), which activates the cGAS–STING (cyclic GMP-AMP synthase-stimulator of interferon genes) pathway and promotes the production of inflammatory factors and breast cancer metastasis. However...

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Detalles Bibliográficos
Autores principales: Duan, Dandan, Shang, Mengjie, Han, Yanxu, Liu, Jiayuan, Liu, Jiwei, Kong, Sun Hyok, Hou, Jingyao, Huang, Baiqu, Lu, Jun, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836657/
https://www.ncbi.nlm.nih.gov/pubmed/35163710
http://dx.doi.org/10.3390/ijms23031788