Asymmetric Notch activity by differential inheritance of lysosomes in human neural stem cells

Symmetric and asymmetric cell divisions are conserved strategies for stem cell expansion and the generation of more committed progeny, respectively. Here, we demonstrate that in human neural stem cells (NSCs), lysosomes are asymmetrically inherited during mitosis. We show that lysosomes contain Notc...

Descripción completa

Detalles Bibliográficos
Autores principales: Bohl, Bettina, Jabali, Ammar, Ladewig, Julia, Koch, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836802/
https://www.ncbi.nlm.nih.gov/pubmed/35148180
http://dx.doi.org/10.1126/sciadv.abl5792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836802/
https://www.ncbi.nlm.nih.gov/pubmed/35148180
http://dx.doi.org/10.1126/sciadv.abl5792

Ejemplares similares