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The Expression of TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Can Be Controlled by the Antioxidant Orchestrator NRF2 in Human Carcinoma Cells

Hyperactivation of the KEAP1-NRF2 axis is a common molecular trait in carcinomas from different origin. The transcriptional program induced by NRF2 involves antioxidant and metabolic genes that render cancer cells more capable of dealing with oxidative stress. The TP53-Induced Glycolysis and Apoptos...

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Detalles Bibliográficos
Autores principales: Simon-Molas, Helga, Sánchez-de-Diego, Cristina, Navarro-Sabaté, Àurea, Castaño, Esther, Ventura, Francesc, Bartrons, Ramon, Manzano, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836827/
https://www.ncbi.nlm.nih.gov/pubmed/35163828
http://dx.doi.org/10.3390/ijms23031905