Novel Aurora A Kinase Inhibitor Fangchinoline Enhances Cisplatin–DNA Adducts and Cisplatin Therapeutic Efficacy in OVCAR-3 Ovarian Cancer Cells-Derived Xenograft Model

Aurora A kinase (Aurora A) is a serine/threonine kinase regulating control of multiple events during cell-cycle progression. Playing roles in promoting proliferation and inhibiting cell death in cancer cells leads Aurora A to become a target for cancer therapy. It is overexpressed and associated wit...

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Detalles Bibliográficos
Autores principales: Winardi, Daniel, Chu, Pei-Yi, Chen, Guan-Yu, Wang, Ke, Hsu, Wei-Yu, Hsieh, Ching-Liang, Chen, Yung-Hsiang, Wu, Yang-Chang, Yang, Juan-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836832/
https://www.ncbi.nlm.nih.gov/pubmed/35163790
http://dx.doi.org/10.3390/ijms23031868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836832/
https://www.ncbi.nlm.nih.gov/pubmed/35163790
http://dx.doi.org/10.3390/ijms23031868

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