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Circulating Small Extracellular Vesicles May Contribute to Vaso-Occlusive Crises in Sickle Cell Disease

We previously found that the plasma of patients with sickle cell disease (SCD) contains large numbers of small extracellular vesicles (EVs) and that the EVs disrupt the integrity of endothelial cell monolayers (especially if obtained during episodes of acute chest syndrome, ACS). The present study w...

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Detalles Bibliográficos
Autores principales: Gemel, Joanna, Zhang, Jared, Mao, Yifan, Lapping-Carr, Gabrielle, Beyer, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836895/
https://www.ncbi.nlm.nih.gov/pubmed/35160266
http://dx.doi.org/10.3390/jcm11030816