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Granzymes: The Molecular Executors of Immune-Mediated Cytotoxicity

Cytotoxic T lymphocytes, differentiated CD8+ T cells, use multiple mechanisms to mediate their function, including release of granules containing perforin and granzymes at target cells. Granzymes are a family of cytotoxic proteases that each act on unique sets of biological substrates within target...

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Detalles Bibliográficos
Autores principales: Hay, Zachary L. Z., Slansky, Jill E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836949/
https://www.ncbi.nlm.nih.gov/pubmed/35163755
http://dx.doi.org/10.3390/ijms23031833