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Granzymes: The Molecular Executors of Immune-Mediated Cytotoxicity
Cytotoxic T lymphocytes, differentiated CD8+ T cells, use multiple mechanisms to mediate their function, including release of granules containing perforin and granzymes at target cells. Granzymes are a family of cytotoxic proteases that each act on unique sets of biological substrates within target...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8836949/ https://www.ncbi.nlm.nih.gov/pubmed/35163755 http://dx.doi.org/10.3390/ijms23031833 |