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Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections

We previously reported higher ACE2 levels in smokers and patients with COPD. The current study investigates if patients with interstitial lung diseases (ILDs) such as IPF and LAM have elevated ACE2, TMPRSS2, and Furin levels, increasing their risk for SARS-CoV-2 infection and development of COVID-19...

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Detalles Bibliográficos
Autores principales: Lu, Wenying, Eapen, Mathew Suji, Singhera, Gurpreet Kaur, Markos, James, Haug, Greg, Chia, Collin, Larby, Josie, Brake, Samuel James, Westall, Glen P., Jaffar, Jade, Kalidhindi, Rama Satyanarayana Raju, Fonseka, Nimesha De, Sathish, Venkatachalem, Hackett, Tillie L., Sohal, Sukhwinder Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837032/
https://www.ncbi.nlm.nih.gov/pubmed/35160229
http://dx.doi.org/10.3390/jcm11030777