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Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections
We previously reported higher ACE2 levels in smokers and patients with COPD. The current study investigates if patients with interstitial lung diseases (ILDs) such as IPF and LAM have elevated ACE2, TMPRSS2, and Furin levels, increasing their risk for SARS-CoV-2 infection and development of COVID-19...
Autores principales: | Lu, Wenying, Eapen, Mathew Suji, Singhera, Gurpreet Kaur, Markos, James, Haug, Greg, Chia, Collin, Larby, Josie, Brake, Samuel James, Westall, Glen P., Jaffar, Jade, Kalidhindi, Rama Satyanarayana Raju, Fonseka, Nimesha De, Sathish, Venkatachalem, Hackett, Tillie L., Sohal, Sukhwinder Singh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837032/ https://www.ncbi.nlm.nih.gov/pubmed/35160229 http://dx.doi.org/10.3390/jcm11030777 |
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