Identification of Corosolic and Oleanolic Acids as Molecules Antagonizing the Human RORγT Nuclear Receptor Using the Calculated Fingerprints of the Molecular Similarity

RORγT is a protein product of the RORC gene belonging to the nuclear receptor subfamily of retinoic-acid-receptor-related orphan receptors (RORs). RORγT is preferentially expressed in Th17 lymphocytes and drives their differentiation from naive CD4+ cells and is involved in the regulation of the exp...

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Detalles Bibliográficos
Autores principales: Pastwińska, Joanna, Karaś, Kaja, Sałkowska, Anna, Karwaciak, Iwona, Chałaśkiewicz, Katarzyna, Wojtczak, Błażej A., Bachorz, Rafał A., Ratajewski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837092/
https://www.ncbi.nlm.nih.gov/pubmed/35163824
http://dx.doi.org/10.3390/ijms23031906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837092/
https://www.ncbi.nlm.nih.gov/pubmed/35163824
http://dx.doi.org/10.3390/ijms23031906

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