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mTOR Signaling Components in Tumor Mechanobiology

Mechanistic target of rapamycin (mTOR) is a central signaling hub that integrates networks of nutrient availability, cellular metabolism, and autophagy in eukaryotic cells. mTOR kinase, along with its upstream regulators and downstream substrates, is upregulated in most human malignancies. At the sa...

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Detalles Bibliográficos
Autores principales: Gargalionis, Antonios N., Papavassiliou, Kostas A., Basdra, Efthimia K., Papavassiliou, Athanasios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837098/
https://www.ncbi.nlm.nih.gov/pubmed/35163745
http://dx.doi.org/10.3390/ijms23031825