Drug Repurposing of the Unithiol: Inhibition of Metallo-β-Lactamases for the Treatment of Carbapenem-Resistant Gram-Negative Bacterial Infections

The increasing antibiotic resistance is a clinical problem worldwide. Numerous Gram-negative bacteria have already become resistant to the most widely used class of antibacterial drugs, β-lactams. One of the main mechanisms is inactivation of β-lactam antibiotics by bacterial β-lactamases. Appearanc...

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Detalles Bibliográficos
Autores principales: Grigorenko, Vitaly G., Khrenova, Maria G., Andreeva, Irina P., Rubtsova, Maya Yu., Lev, Anastasia I., Novikova, Tatiana S., Detusheva, Elena V., Fursova, Nadezhda K., Dyatlov, Ivan A., Egorov, Alexey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837113/
https://www.ncbi.nlm.nih.gov/pubmed/35163756
http://dx.doi.org/10.3390/ijms23031834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837113/
https://www.ncbi.nlm.nih.gov/pubmed/35163756
http://dx.doi.org/10.3390/ijms23031834

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