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Mechanism of Caspase-1 Inhibition by Four Anti-inflammatory Drugs Used in COVID-19 Treatment

The inflammatory protease caspase-1 is associated with the release of cytokines. An excessive number of cytokines (a “cytokine storm”) is a dangerous consequence of COVID-19 infection and has been indicated as being among the causes of death by COVID-19. The anti-inflammatory drug colchicine (which...

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Detalles Bibliográficos
Autores principales: Caruso, Francesco, Pedersen, Jens Z., Incerpi, Sandra, Kaur, Sarjit, Belli, Stuart, Florea, Radu-Mihai, Rossi, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837144/
https://www.ncbi.nlm.nih.gov/pubmed/35163769
http://dx.doi.org/10.3390/ijms23031849