The Anxiolytic Drug Buspirone Prevents Rotenone-Induced Toxicity in a Mouse Model of Parkinson’s Disease

A pharmacological and genetic blockade of the dopamine D3 receptor (D3R) has shown to be neuroprotective in models of Parkinson’s disease (PD). The anxiolytic drug buspirone, a serotonin receptor 1A agonist, also functions as a potent D3R antagonist. To test if buspirone elicited neuroprotective act...

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Detalles Bibliográficos
Autores principales: Thomas Broome, Sarah, Castorina, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837189/
https://www.ncbi.nlm.nih.gov/pubmed/35163768
http://dx.doi.org/10.3390/ijms23031845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837189/
https://www.ncbi.nlm.nih.gov/pubmed/35163768
http://dx.doi.org/10.3390/ijms23031845

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