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Topoisomerase VI is a chirally-selective, preferential DNA decatenase

DNA topoisomerase VI (topo VI) is a type IIB DNA topoisomerase found predominantly in archaea and some bacteria, but also in plants and algae. Since its discovery, topo VI has been proposed to be a DNA decatenase; however, robust evidence and a mechanism for its preferential decatenation activity wa...

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Detalles Bibliográficos
Autores principales: McKie, Shannon J, Desai, Parth Rakesh, Seol, Yeonee, Allen, Adam MB, Maxwell, Anthony, Neuman, Keir C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837201/
https://www.ncbi.nlm.nih.gov/pubmed/35076393
http://dx.doi.org/10.7554/eLife.67021