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The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates

Catch bonds are a form of mechanoregulation wherein protein-ligand interactions are strengthened by the application of dissociative tension. Currently, the best-characterized examples of catch bonds are between single protein-ligand pairs. The essential AAA (ATPase associated with diverse cellular a...

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Detalles Bibliográficos
Autores principales: Mickolajczyk, Keith J, Olinares, Paul Dominic B, Chait, Brian T, Liu, Shixin, Kapoor, Tarun M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837202/
https://www.ncbi.nlm.nih.gov/pubmed/35147499
http://dx.doi.org/10.7554/eLife.73534