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Crocin ameliorates atherosclerosis by promoting the reverse cholesterol transport and inhibiting the foam cell formation via regulating PPARγ/LXR-α

Crocin (CRO) is feasible in alleviating atherosclerosis (AS), the mechanism of which was therefore explored in the study. High-fat diet (HFD)-induced apolipoprotein E-deficient (ApoE(−/−)) mice and lysophosphatidic acid (LPA)-treated macrophages received CRO treatment. Treated macrophage viability w...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Liu, Peng, He, Zhaopeng, Zhang, like, He, Xinqi, Liu, Feng, Qi, Jinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837240/
https://www.ncbi.nlm.nih.gov/pubmed/34978526
http://dx.doi.org/10.1080/15384101.2021.2015669