BioPhi: A platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning

Despite recent advances in transgenic animal models and display technologies, humanization of mouse sequences remains one of the main routes for therapeutic antibody development. Traditionally, humanization is manual, laborious, and requires expert knowledge. Although automation efforts are advancin...

Descripción completa

Detalles Bibliográficos
Autores principales: Prihoda, David, Maamary, Jad, Waight, Andrew, Juan, Veronica, Fayadat-Dilman, Laurence, Svozil, Daniel, Bitton, Danny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837241/
https://www.ncbi.nlm.nih.gov/pubmed/35133949
http://dx.doi.org/10.1080/19420862.2021.2020203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837241/
https://www.ncbi.nlm.nih.gov/pubmed/35133949
http://dx.doi.org/10.1080/19420862.2021.2020203

Ejemplares similares