T-SIGn tumor reengineering therapy and CAR T cells synergize in combination therapy to clear human lung tumor xenografts and lung metastases in NSG mice

Although chimeric antigen receptor (CAR) T cells have emerged as highly effective treatments for patients with hematologic malignancies, similar efficacy has not been achieved in the context of solid tumors. There are several reasons for this disparity including a) fewer solid tumor target antigens,...

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Detalles Bibliográficos
Autores principales: Sonzogni, Olmo, Zak, Daniel E., Sasso, Maria Stella, Lear, Rochelle, Muntzer, Alice, Zonca, Manuela, West, Katy, Champion, Brian R., Rottman, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837249/
https://www.ncbi.nlm.nih.gov/pubmed/35154906
http://dx.doi.org/10.1080/2162402X.2022.2029070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837249/
https://www.ncbi.nlm.nih.gov/pubmed/35154906
http://dx.doi.org/10.1080/2162402X.2022.2029070

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