HLA imputation and its application to genetic and molecular fine-mapping of the MHC region in autoimmune diseases

Variations of human leukocyte antigen (HLA) genes in the major histocompatibility complex region (MHC) significantly affect the risk of various diseases, especially autoimmune diseases. Fine-mapping of causal variants in this region was challenging due to the difficulty in sequencing and its inappli...

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Detalles Bibliográficos
Autores principales: Naito, Tatsuhiko, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837514/
https://www.ncbi.nlm.nih.gov/pubmed/34786601
http://dx.doi.org/10.1007/s00281-021-00901-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837514/
https://www.ncbi.nlm.nih.gov/pubmed/34786601
http://dx.doi.org/10.1007/s00281-021-00901-9

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