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HLA imputation and its application to genetic and molecular fine-mapping of the MHC region in autoimmune diseases
Variations of human leukocyte antigen (HLA) genes in the major histocompatibility complex region (MHC) significantly affect the risk of various diseases, especially autoimmune diseases. Fine-mapping of causal variants in this region was challenging due to the difficulty in sequencing and its inappli...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837514/ https://www.ncbi.nlm.nih.gov/pubmed/34786601 http://dx.doi.org/10.1007/s00281-021-00901-9 |