Influence of breast cancer risk factors on proliferation and DNA damage in human breast glandular tissues: role of intracellular estrogen levels, oxidative stress and estrogen biotransformation

Breast cancer etiology is associated with both proliferation and DNA damage induced by estrogens. Breast cancer risk factors (BCRF) such as body mass index (BMI), smoking, and intake of estrogen-active drugs were recently shown to influence intratissue estrogen levels. Thus, the aim of the present s...

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Detalles Bibliográficos
Autores principales: Wunder, Juliane, Pemp, Daniela, Cecil, Alexander, Mahdiani, Maryam, Hauptstein, René, Schmalbach, Katja, Geppert, Leo N., Ickstadt, Katja, Esch, Harald L., Dandekar, Thomas, Lehmann, Leane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Genotoxicity and Carcinogenicity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837527/
https://www.ncbi.nlm.nih.gov/pubmed/34921608
http://dx.doi.org/10.1007/s00204-021-03198-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837527/
https://www.ncbi.nlm.nih.gov/pubmed/34921608
http://dx.doi.org/10.1007/s00204-021-03198-7

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