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Review of applications and challenges of quantitative systems pharmacology modeling and machine learning for heart failure

Quantitative systems pharmacology (QSP) is an important approach in pharmaceutical research and development that facilitates in silico generation of quantitative mechanistic hypotheses and enables in silico trials. As demonstrated by applications from numerous industry groups and interest from regul...

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Detalles Bibliográficos
Autores principales: Cheng, Limei, Qiu, Yuchi, Schmidt, Brian J., Wei, Guo-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837528/
https://www.ncbi.nlm.nih.gov/pubmed/34637069
http://dx.doi.org/10.1007/s10928-021-09785-6