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Review of applications and challenges of quantitative systems pharmacology modeling and machine learning for heart failure
Quantitative systems pharmacology (QSP) is an important approach in pharmaceutical research and development that facilitates in silico generation of quantitative mechanistic hypotheses and enables in silico trials. As demonstrated by applications from numerous industry groups and interest from regul...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837528/ https://www.ncbi.nlm.nih.gov/pubmed/34637069 http://dx.doi.org/10.1007/s10928-021-09785-6 |