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Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia

Ectodysplasin A receptor (EDAR) is a death receptor in the Tumour Necrosis Factor Receptor (TNFR) superfamily with roles in the development of hair follicles, teeth and cutaneous glands. Here we report that human Oestrogen Receptor (ER) negative breast carcinomas which display squamous differentiati...

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Detalles Bibliográficos
Autores principales: Williams, Rebecca, Jobling, Stephanie, Sims, Andrew H., Mou, Chunyan, Wilkinson, Lorna, Collu, Giovanna M., Streuli, Charles H., Gilmore, Andrew P., Headon, Denis J., Brennan, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837535/
https://www.ncbi.nlm.nih.gov/pubmed/34916592
http://dx.doi.org/10.1038/s41388-021-01902-6