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Elevated EDAR signalling promotes mammary gland tumourigenesis with squamous metaplasia
Ectodysplasin A receptor (EDAR) is a death receptor in the Tumour Necrosis Factor Receptor (TNFR) superfamily with roles in the development of hair follicles, teeth and cutaneous glands. Here we report that human Oestrogen Receptor (ER) negative breast carcinomas which display squamous differentiati...
Autores principales: | Williams, Rebecca, Jobling, Stephanie, Sims, Andrew H., Mou, Chunyan, Wilkinson, Lorna, Collu, Giovanna M., Streuli, Charles H., Gilmore, Andrew P., Headon, Denis J., Brennan, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837535/ https://www.ncbi.nlm.nih.gov/pubmed/34916592 http://dx.doi.org/10.1038/s41388-021-01902-6 |
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