The androgen receptor—lncRNASAT1-AKT-p15 axis mediates androgen-induced cellular senescence in prostate cancer cells

The bipolar androgen therapy (BAT) to treat prostate cancer (PCa) includes cycles of supraphysiological androgen levels (SAL) under androgen-deprivation therapy (ADT). We showed previously that SAL induces cellular senescence in androgen-sensitive PCa cells and in ex vivo-treated patient PCa tumor s...

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Detalles Bibliográficos
Autores principales: Mirzakhani, Kimia, Kallenbach, Julia, Rasa, Seyed Mohammad Mahdi, Ribaudo, Federico, Ungelenk, Martin, Ehsani, Marzieh, Gong, Wenrong, Gassler, Nikolaus, Leeder, Mirjam, Grimm, Marc-Oliver, Neri, Francesco, Baniahmad, Aria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837536/
https://www.ncbi.nlm.nih.gov/pubmed/34667276
http://dx.doi.org/10.1038/s41388-021-02060-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837536/
https://www.ncbi.nlm.nih.gov/pubmed/34667276
http://dx.doi.org/10.1038/s41388-021-02060-5

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