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The androgen receptor—lncRNASAT1-AKT-p15 axis mediates androgen-induced cellular senescence in prostate cancer cells

The bipolar androgen therapy (BAT) to treat prostate cancer (PCa) includes cycles of supraphysiological androgen levels (SAL) under androgen-deprivation therapy (ADT). We showed previously that SAL induces cellular senescence in androgen-sensitive PCa cells and in ex vivo-treated patient PCa tumor s...

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Detalles Bibliográficos
Autores principales:	Mirzakhani, Kimia, Kallenbach, Julia, Rasa, Seyed Mohammad Mahdi, Ribaudo, Federico, Ungelenk, Martin, Ehsani, Marzieh, Gong, Wenrong, Gassler, Nikolaus, Leeder, Mirjam, Grimm, Marc-Oliver, Neri, Francesco, Baniahmad, Aria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837536/ https://www.ncbi.nlm.nih.gov/pubmed/34667276 http://dx.doi.org/10.1038/s41388-021-02060-5

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