Regulation of Src tumor activity by its N-terminal intrinsically disordered region

The membrane-anchored Src tyrosine kinase is involved in numerous pathways and its deregulation is involved in human cancer. Our knowledge on Src regulation relies on crystallography, which revealed intramolecular interactions to control active Src conformations. However, Src contains a N-terminal i...

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Detalles Bibliográficos
Autores principales: Aponte, Emilie, Lafitte, Marie, Sirvent, Audrey, Simon, Valérie, Barbery, Maud, Fourgous, Elise, Boublik, Yvan, Maffei, Mariano, Armand, Florence, Hamelin, Romain, Pannequin, Julie, Fort, Philippe, Pons, Miquel, Roche, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837538/
https://www.ncbi.nlm.nih.gov/pubmed/34999732
http://dx.doi.org/10.1038/s41388-021-02092-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837538/
https://www.ncbi.nlm.nih.gov/pubmed/34999732
http://dx.doi.org/10.1038/s41388-021-02092-x

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