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Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine

PURPOSE: This study establishes a multiphysics simulation platform for both conventional and targeted thrombolysis using tissue plasminogen activator (tPA). Based on our computational results, the effects of therapeutic parameters on the dynamics of thrombolysis and the risk of side effects are inve...

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Detalles Bibliográficos
Autores principales: Gu, Boram, Huang, Yu, Manchester, Emily Louise, Hughes, Alun D., Thom, Simon A. McG., Chen, Rongjun, Xu, Xiao Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837543/
https://www.ncbi.nlm.nih.gov/pubmed/35044591
http://dx.doi.org/10.1007/s11095-021-03161-2