Cargando…
Biallelic mutations in cancer genomes reveal local mutational determinants
The infinite sites model of molecular evolution posits that every position in the genome is mutated at most once(1). By restricting the number of possible mutation histories, haplotypes and alleles, it forms a cornerstone of tumor phylogenetic analysis(2) and is often implied when calling, phasing a...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837546/ https://www.ncbi.nlm.nih.gov/pubmed/35145300 http://dx.doi.org/10.1038/s41588-021-01005-8 |