Functional interrogation of autoimmune disease genetics using CRISPR/Cas9 technologies and massively parallel reporter assays

Genetic studies, including genome-wide association studies, have identified many common variants that are associated with autoimmune diseases. Strikingly, in addition to being frequently observed in healthy individuals, a number of these variants are shared across diseases with diverse clinical pres...

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Detalles Bibliográficos
Autores principales: Ding, James, Frantzeskos, Antonios, Orozco, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837574/
https://www.ncbi.nlm.nih.gov/pubmed/34508276
http://dx.doi.org/10.1007/s00281-021-00887-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837574/
https://www.ncbi.nlm.nih.gov/pubmed/34508276
http://dx.doi.org/10.1007/s00281-021-00887-4

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