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Methods for statistical fine-mapping and their applications to auto-immune diseases

Although genome-wide association studies (GWAS) have identified thousands of loci in the human genome that are associated with different traits, understanding the biological mechanisms underlying the association signals identified in GWAS remains challenging. Statistical fine-mapping is a method aim...

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Detalles Bibliográficos
Autores principales: Wang, Qingbo S., Huang, Hailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837575/
https://www.ncbi.nlm.nih.gov/pubmed/35041074
http://dx.doi.org/10.1007/s00281-021-00902-8