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In vitro reconstitution of an efficient nucleotide excision repair system using mesophilic enzymes from Deinococcus radiodurans

Nucleotide excision repair (NER) is a universal and versatile DNA repair pathway, capable of removing a very wide range of lesions, including UV-induced pyrimidine dimers and bulky adducts. In bacteria, NER involves the sequential action of the UvrA, UvrB and UvrC proteins to release a short 12- or...

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Detalles Bibliográficos
Autores principales: Seck, Anna, De Bonis, Salvatore, Saint-Pierre, Christine, Gasparutto, Didier, Ravanat, Jean-Luc, Timmins, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837605/
https://www.ncbi.nlm.nih.gov/pubmed/35149830
http://dx.doi.org/10.1038/s42003-022-03064-x