ASCL1 phosphorylation and ID2 upregulation are roadblocks to glioblastoma stem cell differentiation

The growth of glioblastoma (GBM), one of the deadliest adult cancers, is fuelled by a subpopulation of stem/progenitor cells, which are thought to be the source of resistance and relapse after treatment. Re-engagement of a latent capacity of these cells to re-enter a trajectory resulting in cell dif...

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Detalles Bibliográficos
Autores principales: Azzarelli, Roberta, McNally, Aoibheann, Dell’Amico, Claudia, Onorati, Marco, Simons, Benjamin, Philpott, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837758/
https://www.ncbi.nlm.nih.gov/pubmed/35149717
http://dx.doi.org/10.1038/s41598-022-06248-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837758/
https://www.ncbi.nlm.nih.gov/pubmed/35149717
http://dx.doi.org/10.1038/s41598-022-06248-x

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