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Suppression of tumor metastasis by a RECK-activating small molecule

RECK encodes a membrane-anchored protease-regulator which is often downregulated in a wide variety of cancers, and reduced RECK expression often correlates with poorer prognoses. In mouse models, forced expression of RECK in tumor xenografts results in suppression of tumor angiogenesis, invasion, an...

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Detalles Bibliográficos
Autores principales: Yoshida, Yoko, Yuki, Kanako, Dan, Shingo, Yamazaki, Kanami, Noda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837781/
https://www.ncbi.nlm.nih.gov/pubmed/35149728
http://dx.doi.org/10.1038/s41598-022-06288-3