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YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription

Yes-associated protein (YAP) activation is crucial for tumor formation and development, and its stability is regulated by ubiquitination. ISGylation is a type of ubiquitination like post-translational modification, whereas whether YAP is ISGylated and how ISGylation influences YAP ubiquitination-rel...

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Detalles Bibliográficos
Autores principales: Xue, Xiangfei, Tian, Xiaoting, Zhang, Congcong, Miao, Yayou, Wang, Yikun, Peng, Yingxiu, Qiu, Shiyu, Wang, Hong, Cui, Jiangtao, Cao, Leiqun, Sun, Fenyong, Qiao, Yongxia, Zhang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837792/
https://www.ncbi.nlm.nih.gov/pubmed/35149670
http://dx.doi.org/10.1038/s41420-022-00842-8