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YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription
Yes-associated protein (YAP) activation is crucial for tumor formation and development, and its stability is regulated by ubiquitination. ISGylation is a type of ubiquitination like post-translational modification, whereas whether YAP is ISGylated and how ISGylation influences YAP ubiquitination-rel...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837792/ https://www.ncbi.nlm.nih.gov/pubmed/35149670 http://dx.doi.org/10.1038/s41420-022-00842-8 |