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Development of an in vitro model for animal species susceptibility to SARS-CoV-2 replication based on expression of ACE2 and TMPRSS2 in avian cells

The SARS-CoV-2 (SARS-CoV-2) virus has caused a worldwide pandemic because of the virus's ability to transmit efficiently human-to-human. A key determinant of infection is the attachment of the viral spike protein to the host receptor angiotensin-converting enzyme 2 (ACE2). Because of the presum...

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Detalles Bibliográficos
Autores principales: Kapczynski, Darrell R., Sweeney, Ryan, Spackman, Erica, Pantin-Jackwood, Mary, Suarez, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837912/
https://www.ncbi.nlm.nih.gov/pubmed/35217403
http://dx.doi.org/10.1016/j.virol.2022.01.014