The Reductive Dehydroxylation Catalyzed by IspH, a Source of Inspiration for the Development of Novel Anti-Infectives

The non-mevalonate or also called MEP pathway is an essential route for the biosynthesis of isoprenoid precursors in most bacteria and in microorganisms belonging to the Apicomplexa phylum, such as the parasite responsible for malaria. The absence of this pathway in mammalians makes it an interestin...

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Detalles Bibliográficos
Autores principales: Jobelius, Hannah, Bianchino, Gabriella Ines, Borel, Franck, Chaignon, Philippe, Seemann, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837944/
https://www.ncbi.nlm.nih.gov/pubmed/35163971
http://dx.doi.org/10.3390/molecules27030708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837944/
https://www.ncbi.nlm.nih.gov/pubmed/35163971
http://dx.doi.org/10.3390/molecules27030708

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