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The Reductive Dehydroxylation Catalyzed by IspH, a Source of Inspiration for the Development of Novel Anti-Infectives
The non-mevalonate or also called MEP pathway is an essential route for the biosynthesis of isoprenoid precursors in most bacteria and in microorganisms belonging to the Apicomplexa phylum, such as the parasite responsible for malaria. The absence of this pathway in mammalians makes it an interestin...
Autores principales: | Jobelius, Hannah, Bianchino, Gabriella Ines, Borel, Franck, Chaignon, Philippe, Seemann, Myriam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8837944/ https://www.ncbi.nlm.nih.gov/pubmed/35163971 http://dx.doi.org/10.3390/molecules27030708 |
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