Solubility and Dissolution Enhancement of Dexibuprofen with Hydroxypropylbetacyclodextrin (HPβCD) and Poloxamers (188/407) Inclusion Complexes: Preparation and In Vitro Characterization

The objective of this study was to improve the dissolution and solubility of dexibuprofen (DEX) using hydroxypropyl beta cyclodextrin (HPβCD) inclusion complexes and also to evaluate the effect of presence of hydrophilic polymers on solubilization efficiency of HPβCD. Three different methods (physic...

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Detalles Bibliográficos
Autores principales: Munir, Rabia, Hadi, Abdul, Khan, Salah-ud-Din, Asghar, Sajid, Irfan, Muhammad, Khan, Ikram Ullah, Hameed, Misbah, Inam, Sana, Islam, Nayyer, Hassan, Shahzadi Filza, Ishtiaq, Memoona, Akhtar Shah, Pervaiz, Iqbal, Muhammad Shahid, Khalid Syed, Haroon, Khames, Ahmed, A. S. Abourehab, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838044/
https://www.ncbi.nlm.nih.gov/pubmed/35160569
http://dx.doi.org/10.3390/polym14030579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838044/
https://www.ncbi.nlm.nih.gov/pubmed/35160569
http://dx.doi.org/10.3390/polym14030579

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