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Effects of Roxadustat on Erythropoietin Production in the Rat Body

Anemia is a major complication of chronic renal failure. To treat this anemia, prolylhydroxylase domain enzyme (PHD) inhibitors as well as erythropoiesis-stimulating agents (ESAs) have been used. Although PHD inhibitors rapidly stimulate erythropoietin (Epo) production, the precise sites of Epo prod...

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Detalles Bibliográficos
Autores principales: Yasuoka, Yukiko, Izumi, Yuichiro, Fukuyama, Takashi, Omiya, Haruki, Pham, Truyen D., Inoue, Hideki, Oshima, Tomomi, Yamazaki, Taiga, Uematsu, Takayuki, Kobayashi, Noritada, Shimada, Yoshitaka, Nagaba, Yasushi, Yamashita, Tetsuro, Mukoyama, Masashi, Sato, Yuichi, Wall, Susan M., Sands, Jeff M., Takahashi, Noriko, Kawahara, Katsumasa, Nonoguchi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838165/
https://www.ncbi.nlm.nih.gov/pubmed/35164384
http://dx.doi.org/10.3390/molecules27031119