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Doxorubicin-Loaded Metal-Organic Framework Nanoparticles as Acid-Activatable Hydroxyl Radical Nanogenerators for Enhanced Chemo/Chemodynamic Synergistic Therapy

Doxorubicin (DOX) is a widely used first-line antitumor agent; however, acquired drug resistance and side effects have become the main challenges to effective cancer therapy. Herein, DOX is loaded into iron-rich metal–organic framework/tannic acid (TA) nanocomplex to form a tumor-targeting and acid-...

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Detalles Bibliográficos
Autores principales: Li, Honghui, Zhang, Ying, Liang, Lingxia, Song, Jiaxing, Wei, Zixuan, Yang, Shuyue, Ma, Yunong, Chen, Wei R., Lu, Cuixia, Wen, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838206/
https://www.ncbi.nlm.nih.gov/pubmed/35161041
http://dx.doi.org/10.3390/ma15031096