Targeting Cytotoxin-Associated Antigen A, a Virulent Factor of Helicobacter pylori-Associated Gastric Cancer: Structure-Based In Silico Screening of Natural Compounds

Gastric cancer is the fifth most frequent cancer and the third major cause of mortality worldwide. Helicobacter pylori, a bacterial infection linked with GC, injects the cytotoxin-associated antigen A (CagA; an oncoprotein) into host cells. When the phosphorylated CagA protein enters the cell, it at...

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Detalles Bibliográficos
Autores principales: He, Shan, Almalki, Abdulraheem Ali, Rafeeq, Misbahuddin M., Sain, Ziaullah M., Alqosaibi, Amany I., Alnamshan, Mashael M., Al-Dhuayan, Ibtesam S., Rahaman, Abdul, Zhang, Yang, Banjer, Hamsa Jameel, Anjum, Farah, Alzghaibi, Haitham Ali M., Alharbi, Ali H., Jamal, Qazi Mohammad Sajid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838247/
https://www.ncbi.nlm.nih.gov/pubmed/35164000
http://dx.doi.org/10.3390/molecules27030732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838247/
https://www.ncbi.nlm.nih.gov/pubmed/35164000
http://dx.doi.org/10.3390/molecules27030732

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