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Targeting Cytotoxin-Associated Antigen A, a Virulent Factor of Helicobacter pylori-Associated Gastric Cancer: Structure-Based In Silico Screening of Natural Compounds
Gastric cancer is the fifth most frequent cancer and the third major cause of mortality worldwide. Helicobacter pylori, a bacterial infection linked with GC, injects the cytotoxin-associated antigen A (CagA; an oncoprotein) into host cells. When the phosphorylated CagA protein enters the cell, it at...
Autores principales: | He, Shan, Almalki, Abdulraheem Ali, Rafeeq, Misbahuddin M., Sain, Ziaullah M., Alqosaibi, Amany I., Alnamshan, Mashael M., Al-Dhuayan, Ibtesam S., Rahaman, Abdul, Zhang, Yang, Banjer, Hamsa Jameel, Anjum, Farah, Alzghaibi, Haitham Ali M., Alharbi, Ali H., Jamal, Qazi Mohammad Sajid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838247/ https://www.ncbi.nlm.nih.gov/pubmed/35164000 http://dx.doi.org/10.3390/molecules27030732 |
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