Molecular Mechanisms of Amylin Turnover, Misfolding and Toxicity in the Pancreas

Amyloidosis is a common pathological event in which proteins self-assemble into misfolded soluble and insoluble molecular forms, oligomers and fibrils that are often toxic to cells. Notably, aggregation-prone human islet amyloid polypeptide (hIAPP), or amylin, is a pancreatic hormone linked to islet...

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Detalles Bibliográficos
Autores principales: Bhowmick, Diti Chatterjee, Kudaibergenova, Zhanar, Burnett, Lydia, Jeremic, Aleksandar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838401/
https://www.ncbi.nlm.nih.gov/pubmed/35164285
http://dx.doi.org/10.3390/molecules27031021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838401/
https://www.ncbi.nlm.nih.gov/pubmed/35164285
http://dx.doi.org/10.3390/molecules27031021

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