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Expression, Purification, and Comparative Inhibition of Helicobacter pylori Urease by Regio-Selectively Alkylated Benzimidazole 2-Thione Derivatives

The urease enzyme has been an important target for the discovery of effective pharmacological and agricultural products. Thirteen regio-selectively alkylated benzimidazole-2-thione derivatives have been designed to carry the essential features of urease inhibitors. The urease enzyme was isolated fro...

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Detalles Bibliográficos
Autores principales: Mohammed, Salih Osman, El Ashry, El Sayed H., Khalid, Asaad, Amer, Mohamed R., Metwaly, Ahmed M., Eissa, Ibrahim H., Elkaeed, Eslam B., Elshobaky, Ahmed, Hafez, Elsayed E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838460/
https://www.ncbi.nlm.nih.gov/pubmed/35164122
http://dx.doi.org/10.3390/molecules27030865