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Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices—A Practical Example

Desorption/ionization mass spectrometry (DI-MS) approaches allow for the rapid quantification of drugs in biological matrices using assays that can be validated according to regulatory guidelines. However, specific adaptations must be applied to create reliable quantification methods, depending on t...

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Detalles Bibliográficos
Autores principales: Fresnais, Margaux, Karabulut, Seda, Abou Zeed, Yasmin, Ungermann, Johannes, Benzel, Julia, Pajtler, Kristian W., Pfister, Stefan M., Haefeli, Walter E., Burhenne, Jürgen, Longuespée, Rémi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8838468/
https://www.ncbi.nlm.nih.gov/pubmed/35163955
http://dx.doi.org/10.3390/molecules27030690